"It's like being in a play; I'm always in a play."

Temple Grandin, the subject of a recent HBO biopic, talked about living life among the "yakkity yaks."

Mostly, though, her advice is simple: It's about hard work. Young children need 20 or 30 hours a week of one-on-one time with a committed teacher or mentor. Money, Ms. Grandin says, should not be an obstacle. If you can't afford a professional teacher, find volunteers through your church or synagogue, she says. Parents need to teach 1950s-style social rules "like please and thank you, basic table manners, how to shop."

There have to be high expectations. She's worried about the "handicapped mentality" that she thinks is increasing. "When I see these kids with 150 IQ and their parents want to put them on Social Security [disability], it drives me nuts." These kids "will come up to the book table and start talking about 'my Aspergers.' Why don't you talk about becoming a chemist, or a computer programmer, or a botanist?"

She continues: "It's important to get these autistic kids out and exposed to stuff. You've got to fill up the database." Silicon Valley and the tech companies are like "heaven on earth for the geeks and the nerds. And I want to see more and more of these smart kids going into the tech industry and inventing things—that's what makes America great."